By E.V. Parfenyuk, N.A. Alyoshina, Yu.S. Antsiferova,N.Yu. Sotnikova

Biomedical & Nanomedical Technologies(B&NT): Concise Monographs Series

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Up to 40 volumes are planned for this concisemonograph series, which focuses on the implementation of variousengineering principles in the conception, design, development,analysis and operation of biomedical, biotechnological and nanotechnology systems and applications.

Abstract: The development of nanosystems fortopical drug delivery to target cells is a promising tool toimprove the drug therapeutic index. Transport systems can bedesigned to control the dispatch of the loaded drug to targetareas, increasing its local concentration and bioavailability,while prolonging its retention, half-life and effectiveness.Therefore, such ‘‘smart’’ nanodevices are able to change radicallythe practice of therapy for a variety of diseases and disorders.The purpose of this book is to present the recent researchdevelopment of nanoparticulate delivery systems for immunemodulating agent, glucosaminyl muramyldipeptides(N-acetylglucosaminyl-Nacetylmuramyl–L-alanyl-D-isoglutamine) orGMDP, which is the main component of bacterial wall with knowntarget of action through NOD2 receptors, with an overlook to theirapplications for treatment of endometriosis, which often results ininfertility. Silica-based nanoparticles have generated asignificant amount of interest because of their inherentproperties.

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Hardcover

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