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ASTM E1759-95
Standard Test Method for Isoaspartic Acid in Proteins Method for the Determination of Asparagine Deamidation Products
4 стр.
Заменен
Печатное изданиеЭлектронный (pdf)
81.12 $ (включая НДС 20%)
Разработчик:
Зарубежные/ASTM
Сборник (ASTM):
11.05 Environmental Assessment, Risk Management and Corrective Action / Оценка состояния окружающей среды, риск-менеджмент и корректирующие мероприятия
Тематика:
Biotechnology
Описание
Область применения

1.1 This test method covers the determination of isoaspartic acid residues in a protein or peptide sample. This test method is applicable for the determination of isoaspartic acid residues in a sample in the range of 2.5-50 [mu]mol/L. Higher concentrations can be determined following dilution. The reported lower range is based on single-operator precision.

1.2 The values stated in SI units are to be regarded as the standard.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Ключевые слова:
Asparagine deamidation products; Bioactive peptide protection; Biological protein activity; C-terminal amide; Deamidation; Isoaspartic acid residue; Microheterogeneity; Pharmaceutical proteins; Polypeptide chain; Protein damage; Residue; asparagine deamidation products-isoaspartic acid residue (in range; 2.5-50 micromoles/L) in proteins, test,;Order Form