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ASTM E993-05
Standard Test Method for Evaluation of Delayed Contact Hypersensitivity (Withdrawn 2010)
5 стр.
Отменен
Печатное изданиеЭлектронный (pdf)
96.72 $ (включая НДС 20%)
Разработчик:
Зарубежные/ASTM
ICS:
11.220 Veterinary. Including equipment specific to veterinary medicine / Ветеринария. Включая специальное ветеринарное оборудование11.100 Laboratory medicine / Лабораторная медицина
Сборник (ASTM):
11.06 Environmental; Biological Effects and Environmental Fate; Industrial Biotechnology / Окружающая среда; Биологические эффекты и трансформация в окружающей среде; Промышленные биотехнологии
Тематика:
Environmental Toxicology
Описание
Причина отмены

This test method determines whether a test substance will elicit delayed-contact hypersensitivity in guinea pigs. The test method is applicable to individual chemical compounds, simple and complex mixtures, and also finished products.

Formerly under the jurisdiction of Committee E47 on Biological Effects and Environmental Fate, this test method was withdrawn in February 2010, because other guidelines currently exists.

Значение и использование

This test method can be used to determine whether a test material will elicit skin sensitization or delayed contact
hypersensitivity in guinea pigs.3 ,4 ,5 ,6

The results of this test method are a good indication of the potential for a given test material to produce delayed contact hypersensitivity in human beings under the appropriate conditions.

This test method can be used as a screening technique before conducting a similar test with human subjects.

Область применения

1.1 This test method determines whether a test substance will elicit delayed-contact hypersensitivity in guinea pigs. The test method is applicable to individual chemical compounds, simple and complex mixtures, and also finished products.

1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Ключевые слова:
delayed contact hypersensitivity; erythema; guinea pigs; hypersensitivity; induction; patches; primary challenge; sensitization; skin