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By Toru Yazawa

Biomedical & Nanomedical Technologies (B&NT): ConciseMonographs Series

Up to 40 volumes are planned for this concise monograph series,which focuses on the implementation of various engineeringprinciples in the conception, design, development, analysis andoperation of biomedical, biotechnological and nanotechnologysystems and applications.

Abstract:  The ultimate aim of this study isto make detrended fluctuation analysis (DFA) useful for everyone.It introduces a practical method for making a device that can checkcyclic rhythm in nature, such as the heartbeat. This book presentsempirical evidence revealed by a modified DFA (mDFA). Aheartbeat-checking algorithm, DFA, was made by Peng et al. in themid-1990s. However, the technique has not been incorporated in adevice for practical use. With a view to creating a device DFA,mDFA was made by modifying Peng’s DFA—and a former graduate student(Katsunori Tanaka) created the program under supervision of theauthor. To verify mDFA, hundreds of cyclic phenomena were studiedand recorded.

Crustacean hearts have more than a 100-year history in biology andphysiology. They are advantageous for conducting experiments suchas isolated-heart electrophysiology. Crustacean hearts are thusgood models for human hearts. DFA techniques are essentially justtools quantifying the state of the heartbeat and its control. Thisbook does not describe details about DFA, but it does describe howmDFA works and it is useful for analyzing fluctuation of variouscyclic behaviors such as heart movements. In conclusion, mDFA is auseful tool for studying the heart function in terms of biomedicaltechnology, engineering and animal physiology.

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Hardcover